Anti-neuroinflammatory Effect of Plantago Major var. Japonica in BV-2 Microglial Cells
نویسندگان
چکیده
منابع مشابه
Effects of Paeonol on Anti-Neuroinflammatory Responses in Microglial Cells
Increasing studies suggest that inflammatory processes in the central nervous system mediated by microglial activation plays an important role in numerous neurodegenerative diseases. Development of planning for microglial suppression is considered a key strategy in the search for neuroprotection. Paeonol is a major phenolic component of Moutan Cortex, widely used as a nutrient supplement in Chi...
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Microglial-mediated neuroinflammation has recently been implicated as one of the important mechanisms responsible for the progression of neurodegenerative diseases. Activated microglia cells produce various neurotoxic factors that are harmful to neurons. Therefore, suppression of the inflammatory response elicited by activated microglia is considered a potential therapeutic target for neurodege...
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Objective(s): The pathophysiology of neurodegenerative diseases is complicated, in which inflammatory reactions play a vital role. Microglia cells activation, an essential process of neuroinflammation, can produce neurotoxic molecules and neurotrophic factors, which aggravate inflammation and neuronal injury. Monascin, a major component of red yeast rice, is an azaphil...
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ژورنال
عنوان ژورنال: Biomedical Science Letters
سال: 2017
ISSN: 2288-7415
DOI: 10.15616/bsl.2017.23.4.411